EntityRisk is a healthcare software company that enables innovators and payers to measure and manage uncertainty in medical treatments and financial outcomes. EntityRisk develops proprietary algorithms and analytical tools to help stakeholders in the healthcare sector—such as pharmaceutical companies, payers, and policy makers—better estimate the individual benefits of treatments using advanced modeling and integrated data sources.
Their core offering is a suite of software solutions that combine clinical trial data, genomic information, and real-world evidence to provide:
- Analysis of current and potential surrogate measures and their links to critical health endpoints for patients and payers
- Customized survival and treatment duration curves at both individual and subpopulation levels
- Scenario planning for both pipeline and inline pharmaceutical assets
- Proprietary event and cash flow forecasting for efficacy-linked financial instruments
- Value modeling focused on enabling innovative healthcare financing and payment schemes
All EntityRisk models are designed to identify risk characteristics and correlations across therapeutic interventions. This approach aims to support the creation of new value-based payment models and performance guarantees, ultimately facilitating financial innovation in how new medicines are brought to market and reimbursed.
How was EntityRisk started?
EntityRisk was founded by a group of experienced health economists and industry leaders, bringing together significant academic and practical expertise. The founding team includes Dana Goldman, Dean at the USC Sol Price School of Public Policy; Darius Lakdawalla, an expert in pharmaceutical development and regulatory innovation at USC; Neal Masia, CEO of EntityRisk and Adjunct Professor at Columbia University; Frank D’Amelio, former CFO at Pfizer Inc.; and Jeff Kindler, CEO of Centrexion Therapeutics and advisor at multiple investment firms. Their backgrounds drive EntityRisk’s focus on rigorous analytics and innovative financial modeling in healthcare.
Who uses EntityRisk?
EntityRisk primarily serves organizations operating in healthcare innovation and reimbursement, including pharmaceutical companies, payers (such as insurers and health plans), and policy makers seeking better ways to assess and manage clinical and financial risks associated with new treatments. The platform is particularly valuable for those developing or evaluating efficacy-linked financial instruments and value-based payment models.
What makes EntityRisk different?
EntityRisk’s differentiated approach lies in its proprietary algorithmic library, which integrates multiple data sources—clinical, genomic, and real-world—to deliver individualized and subpopulation-level insights. This enables more precise scenario planning, value modeling, and risk assessment for healthcare financial decision-making. Their team’s blend of academic and industry experience supports the creation of tools that address complex risk and value challenges in modern healthcare.
For more details, visit their About page.
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