What Does Actipulse Neuroscience Do?

    Learn about what Actipulse Neuroscience does, their innovative home-based brain stimulation technology, competitors, and key company information.

    What Does Actipulse Neuroscience Do?

    Name: Actipulse Neuroscience

    Headquarters: Cambridge, MA, USA

    Employees: 11-50

    Actipulse Neuroscience is a neurotechnology company focused on delivering non-invasive brain stimulation treatments for mental health conditions, primarily depression, through a home-based medical device. Actipulse Neuroscience aims to make hospital-grade brain stimulation accessible and affordable for patients outside traditional clinical settings.

    Their core product is a proprietary brain stimulation device designed to treat Major Depressive Disorder (MDD) from the comfort of a patient's home. This approach addresses the key barriers of traditional non-invasive brain stimulation—namely, high device costs and complex treatment protocols that previously required hospital visits. Actipulse's device is currently in the FDA pivotal phase for depression, and in pilot studies for Alzheimer's and Parkinson's diseases, reflecting a broader ambition in neurological and psychiatric care.

    What technology breakthrough does Actipulse Neuroscience leverage?

    Actipulse Neuroscience utilizes non-invasive brain stimulation technology, a well-established and FDA-cleared method for treating depression. Their innovation lies in miniaturizing and simplifying the technology so it can be used safely and effectively at home, without sacrificing efficacy. This shift could significantly expand access to advanced mental health treatments by lowering both the financial and logistical barriers for patients.

    Who uses Actipulse Neuroscience?

    The primary users of Actipulse’s technology are patients diagnosed with depression, particularly those seeking alternatives to medication or traditional in-clinic therapies. The company is also targeting future applications for patients with Alzheimer's and Parkinson's diseases as they advance clinical trials. Healthcare providers, mental health clinics, and telemedicine platforms may also integrate Actipulse’s home-based solution into their treatment offerings.

    Who are Actipulse Neuroscience's competitors?

    Actipulse Neuroscience operates within the neurotechnology and mental health medical device sector. Notable competitors and adjacent players include:

    • Neuronetics – Known for NeuroStar, an FDA-cleared transcranial magnetic stimulation (TMS) system for depression, primarily used in clinics.
    • BrainsWay – Offers deep TMS systems for depression and obsessive-compulsive disorder (OCD), with a focus on clinical use.
    • Magstim – Provides TMS equipment for hospitals and clinics, focusing on research and clinical treatment settings.

    While these incumbents focus mainly on in-clinic devices, Actipulse differentiates itself by bringing similar technology into the home, aiming to increase accessibility and reduce costs for patients.

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